Postdoctoral Fellows
Graduate Students
Research Assistants
Undergraduate Students
Postdoctoral Fellows
Graduate Students
Research Assistants
Undergraduate Students
The Ehrlich lab’s major research goals are to identify the cellular and molecular interactions between developing T cells and the surrounding thymic stromal cells that govern generation of diverse, non-autoreactive, and non-malignant T cells.
The Ehrlich lab is currently focused on:
· Identifying cellular and molecular mechanisms that induce central tolerance by promoting thymocyte medullary entry and/or interactions with antigen presenting cells
· Determining how age-associated thymic involution impacts thymic stromal cellularity and function, thymocyte development, and the establishment of central tolerance
· Identifying molecular mediators of interactions between T cell acute lymphoblastic leukemia cells and the surrounding tumor microenvironment that promote tumor growth